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The study "Flavoring compounds dominate toxic aldehyde production during e-cigarette vaping" confirms that these toxic aldehydes, such as formaldehyde, are formed not by evaporation, but rather during the chemical breakdown of the flavored e-liquid during the rapid heating process (pyrolysis) that occurs inside e-cigarettes or electronic nicotine delivery systems (ENDS). "How these flavoring compounds in e-cigarette liquids affect the chemical composition and toxicity of the vapor that e-cigarettes produce is practically unknown," explained Andrey Khylstov, Ph.D., an associate research professor of atmospheric sciences at DRI. "Our results show that production of toxic aldehydes is exponentially dependent on the concentration of flavoring compounds." E-cigarette liquids have been marketed in nearly 8,000 different flavors, according to a 2014 report from the World Health Organization. Recent reports have shown that many flavors, such as Gummy Bear, Tutti Fruitty, Bubble Gum, etc., were found to be especially appealing to adolescents and young adults. The U.S. Food and Drug Administration (FDA) reports that 16-percent of high school and 5.3-percent of middle school students were current users of e-cigarettes in 2015, making e-cigarettes the most commonly used tobacco product among youth for the second consecutive year. In 2014, 12.6-percent of U.S. adults had ever tried an e-cigarette, and about 3.7-percent of adults used e-cigarettes daily or some days. Khylstov and his colleagues measured concentrations of 12 aldehydes in aerosols produced by three common e-cigarette devices. To determine whether the flavoring additives affected aldehyde production during vaping, five flavored e-liquids were tested in each device. In addition, two unflavored e-liquids were also tested.
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